About Owen Smith
Owen Smith is a partner at 4BIO Capital, which invests in advanced therapies. He is a director of Estuary Biotherapeutics. Estuary develops genetic medicines for people with serious kidney diseases. Smith is also a board member at Entact Bio.
Experience
This experience comes from official bios and from SEC filings. For roles taken from filings, the years are when the filings name Owen Smith in the role, so the role may have started earlier or lasted longer.
Estuary Biotherapeutics, Inc. Current
Director
2026 – Present · Menlo Park, CA
Estuary develops gene-based medicines for serious kidney disease, with ADPKD as its focus.
Entact Bio, Inc. Current
Board Member
2024 – Present · Watertown, MA
Develops medicines that enhance protein function for people with diseases.
4C
4BIO Capital Current
Partner
Key Colleagues at Startups
The people Owen Smith works with at each company, as listed on that company's latest Form D.
Estuary Biotherapeutics, Inc. · Form D, Oct 16, 2026
Entact Bio, Inc. · Form D, Jun 3, 2026
AS
Andrew Sinclair
Director

Anna French
Director

Pini Orbach
Director

Victoria Richon
CEO, Board Member
RG
Richard Gaster
Director