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Owen Smith

4BIO Capital partner and Estuary Biotherapeutics director.

DirectorRoles at 2 startups
Updated Nov 10, 2026·Latest SEC filing Oct 16, 2026·Suggest an edit

About Owen Smith

Owen Smith is a partner at 4BIO Capital, which invests in advanced therapies. He is a director of Estuary Biotherapeutics. Estuary develops genetic medicines for people with serious kidney diseases. Smith is also a board member at Entact Bio.

Experience

This experience comes from official bios and from SEC filings. For roles taken from filings, the years are when the filings name Owen Smith in the role, so the role may have started earlier or lasted longer.

Estuary Biotherapeutics, Inc. Current
Director
2026 – Present · Menlo Park, CA
Estuary develops gene-based medicines for serious kidney disease, with ADPKD as its focus.
Entact Bio, Inc. Current
Board Member
2024 – Present · Watertown, MA
Develops medicines that enhance protein function for people with diseases.
4BIO Capital Current
Partner

Key Colleagues at Startups

The people Owen Smith works with at each company, as listed on that company's latest Form D.

Estuary Biotherapeutics, Inc. · Form D, Oct 16, 2026
WS
Wayne Sackett
Chief Executive Officer and director
JB
Jacob Bauer
Director
EM
Emily Minkow
Director
Entact Bio, Inc. · Form D, Jun 3, 2026
AS
Anna French
Anna French
Director
Pini Orbach
Pini Orbach
Director
Victoria Richon
Victoria Richon
CEO, Board Member
RG

Owen Smith in the News

Sources

  1. SECEstuary Biotherapeutics, Inc. Form D, filed Oct 16, 2026
  2. SECEntact Bio, Inc. Form D, filed Jun 3, 2026
  3. S3Estuary Biotherapeutics Business Wire release search snippet